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Extensive Focal Epithelial Hyperplasia: A Case Report.

Zahra Mansouri1, Sedigheh Bakhtiari1, Robab Noormohamadi1

  • 1Dept. of Oral Medicine, Dental School, Shahid Beheshti University, Tehran, Iran.

Iranian Journal of Pathology
|September 10, 2015
PubMed
Summary

Focal epithelial hyperplasia (FEH), a rare oral viral infection, presented extensively in an Iranian man with lesions lasting over 25 years. Diagnosis required both clinical observation and histopathological examination for this human papilloma virus manifestation.

Keywords:
Case ReportFocal epithelial hyperplasiaHeck’s disease

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Area of Science:

  • Oral pathology
  • Viral infections
  • Dermatology

Background:

  • Focal epithelial hyperplasia (FEH), also known as Heck's disease, is a rare oral mucosa condition.
  • It is caused by specific human papillomavirus (HPV) subtypes, primarily 13 and 32.
  • The prevalence of FEH varies significantly across different geographic regions and ethnic groups.

Observation:

  • This report details an unusual case of extensive FEH in a 35-year-old Iranian male.
  • The patient's lesions had been present and persistent for over two decades (25 years).
  • Diagnosis was confirmed through a combination of clinical presentation and histopathological analysis.

Findings:

  • The extensive and chronic nature of FEH in this case is noteworthy.
  • Clinical features and histopathological findings were consistent with FEH.
  • The case highlights the diagnostic process for this rare oral condition.

Implications:

  • Dental practitioners must maintain awareness of rare oral lesions like FEH.
  • A combined approach of careful clinical observation and histopathological examination is crucial for accurate FEH diagnosis.
  • Understanding geographic and ethnic variations in FEH frequency is important for public health awareness.