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Related Experiment Video

Updated: Apr 4, 2026

Author Spotlight: Enhancing Visual Outcomes in Cataract Surgery: A Novel Technique to Prevent Posterior Capsular Opacification Through IOL Rotation
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Immediate Sequential Bilateral Cataract Surgery: A Systematic Review and Meta-Analysis.

Line Kessel1, Jens Andresen2, Ditte Erngaard3

  • 1Department of Ophthalmology, Rigshospitalet-Glostrup, 2600 Glostrup, Denmark ; Danish Health and Medicines Authority, 2300 Copenhagen S, Denmark.

Journal of Ophthalmology
|September 10, 2015
PubMed
Summary

Immediate sequential bilateral cataract surgery (ISBCS) shows no difference in complications or visual outcomes compared to separate surgeries. High-quality evidence is lacking, so surgeon-patient discussion is crucial for ISBCS decisions.

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Area of Science:

  • Ophthalmology
  • Surgical Innovation
  • Evidence-Based Medicine

Background:

  • Immediate sequential bilateral cataract surgery (ISBCS) allows both eyes to be operated on the same day.
  • National guidelines are needed to standardize cataract surgery practices.

Purpose of the Study:

  • To review evidence on benefits and harms of ISBCS.
  • To assess complication rates, postoperative anisometropia, and visual function.
  • To inform Danish national guidelines for cataract surgery.

Main Methods:

  • Systematic literature review of PubMed, Embase, and Cochrane databases.
  • Included three randomized controlled trials comparing ISBCS with separate-date bilateral surgery.
  • Meta-analyses conducted using Cochrane Review Manager; evidence quality assessed with GRADE.

Main Results:

  • No significant difference found in complication risk or visual outcomes between ISBCS and separate-date surgery.
  • Evidence quality was rated as low to very low.
  • Postoperative anisometropia prevalence was not reported in the included studies.

Conclusions:

  • Insufficient high-quality evidence prevents evidence-based recommendations for ISBCS.
  • The decision for ISBCS requires careful surgeon-patient consultation.
  • Further high-quality research is needed to establish definitive guidelines.