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Systemic Comorbidity in Children with Cataracts in Nigeria: Advocacy for Rubella Immunization
Roseline Duke1, Sidney Oparah2, Adedayo Adio3
1Department of Ophthalmology, University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria.
Insights
Systemic comorbidities, particularly congenital heart diseases, are frequent in Nigerian children with cataracts. Congenital Rubella Syndrome is a significant cause, highlighting the need for rubella vaccination.
Area of Science:
- Ophthalmology
- Pediatrics
- Cardiology
Background:
- Congenital and developmental cataracts are primary causes of childhood vision impairment.
- These cataracts are often linked to systemic conditions, including congenital heart diseases (CHD), a major cause of childhood mortality.
- Understanding these comorbidities is crucial for comprehensive care.
Purpose of the Study:
- To investigate the pattern of systemic comorbidities in children diagnosed with cataracts in Calabar, Nigeria.
- To identify the prevalence of specific conditions like cardiac anomalies and Congenital Rubella Syndrome.
- To inform public health strategies for preventing childhood vision impairment.
Main Methods:
- A retrospective review of children who underwent cataract surgery between 2011 and 2012.
- Documentation of diagnosed systemic conditions for each child.
- Analysis of the frequency and types of comorbidities observed.
Main Results:
- Out of 66 children, 39.9% had cardiac disease, 24.2% had delayed milestones, and 21.2% had intellectual disability.
- Congenital Rubella Syndrome was confirmed in 45% of the children.
- Common cardiac defects included patent ductus arteriosus (24.2%) and ventricular-septal defect (7.6%).
Conclusions:
- Systemic comorbidities, especially cardiac anomalies, are prevalent in Nigerian children with cataracts.
- Congenital Rubella Syndrome is a significant contributor to childhood cataracts in this region.
- Routine rubella immunization for girls is recommended to reduce the incidence of congenital cataracts.
Abstract:
Background. Congenital and developmental cataracts are leading causes of childhood blindness and severe visual impairment. They may be associated with systemic diseases including congenital heart diseases which are among the major causes of morbidity and mortality in childhood. The pattern of systemic comorbidities seen in children diagnosed with cataract in Calabar, Nigeria, was studied. Methods. A retrospective review was conducted on the children who had cataract surgery between 2011 and 2012. Diagnosis of the systemic condition was documented. Results. A total of 66 children were recruited for the study. Cardiac disease was seen in 26 children (39.9%), followed by delayed milestone in 16 (24.2%), intellectual disability in 14 (21.2%), deafness in 11 (16.7%), epilepsy in 4 (6.1%), and physical handicap in 3 (4.5%) of them. Clinically confirmed Congenital Rubella Syndrome was seen in 30 (45%) of the children. The pattern of CHD seen was as follows: patent ductus arteriosus in 16 (24.2%) followed by ventricular-septal defect in 5 (7.6%), atrial-septal defect in 3 (4.5%), and pulmonary stenosis in 2 (3%). Conclusion. Systemic comorbidities, especially cardiac anomalies, are common among children with cataract in Nigeria. Congenital Rubella Syndrome may be a prominent cause of childhood cataract in our environment. Routine immunization of school girls against rubella is advocated as a measure to mitigate this trend.
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