Systemic Comorbidity in Children with Cataracts in Nigeria: Advocacy for Rubella Immunization

Roseline Duke1, Sidney Oparah2, Adedayo Adio3

  • 1Department of Ophthalmology, University of Calabar Teaching Hospital, Calabar, Cross River State, Nigeria.

Journal of Ophthalmology
|September 10, 2015
PubMed

Insights

Systemic comorbidities, particularly congenital heart diseases, are frequent in Nigerian children with cataracts. Congenital Rubella Syndrome is a significant cause, highlighting the need for rubella vaccination.

Area of Science:

  • Ophthalmology
  • Pediatrics
  • Cardiology

Background:

  • Congenital and developmental cataracts are primary causes of childhood vision impairment.
  • These cataracts are often linked to systemic conditions, including congenital heart diseases (CHD), a major cause of childhood mortality.
  • Understanding these comorbidities is crucial for comprehensive care.

Purpose of the Study:

  • To investigate the pattern of systemic comorbidities in children diagnosed with cataracts in Calabar, Nigeria.
  • To identify the prevalence of specific conditions like cardiac anomalies and Congenital Rubella Syndrome.
  • To inform public health strategies for preventing childhood vision impairment.

Main Methods:

  • A retrospective review of children who underwent cataract surgery between 2011 and 2012.
  • Documentation of diagnosed systemic conditions for each child.
  • Analysis of the frequency and types of comorbidities observed.

Main Results:

  • Out of 66 children, 39.9% had cardiac disease, 24.2% had delayed milestones, and 21.2% had intellectual disability.
  • Congenital Rubella Syndrome was confirmed in 45% of the children.
  • Common cardiac defects included patent ductus arteriosus (24.2%) and ventricular-septal defect (7.6%).

Conclusions:

  • Systemic comorbidities, especially cardiac anomalies, are prevalent in Nigerian children with cataracts.
  • Congenital Rubella Syndrome is a significant contributor to childhood cataracts in this region.
  • Routine rubella immunization for girls is recommended to reduce the incidence of congenital cataracts.

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