Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Adrenal Gland Disorders01:27

Adrenal Gland Disorders

3.9K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
3.9K
Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla01:27

Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla

3.4K
The sympathetic pathways of the collateral ganglia and adrenal medulla serve unique but interconnected roles in the sympathetic response.
Collateral Ganglia
Sympathetic preganglionic axons reach the collateral ganglia along the route of splanchnic nerves. These nerves bypass the sympathetic trunk and communicate with sympathetic postganglionic neurons housed in the prevertebral ganglia. These ganglia supply the organs of the abdominopelvic cavity.
The greater splanchnic nerve, formed by the...
3.4K
Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

70.6K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
70.6K
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

1.4K
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
1.4K
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

732
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
732
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

723
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
723

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genetic Polymorphisms of Vitamin D Receptor and Immune-Metabolic Mechanisms in Recurrent Pregnancy Loss: Narrative Review.

Biology·2026
Same author

Cardiovascular Regulatory Science: Accelerating the Path from Bench to Bedside.

American heart journal·2026
Same author

Early technology review during prototype development and at proof of concept: the case for developing a sequential versus a single-stage approach to early evidence development for health technologies.

International journal of technology assessment in health care·2026
Same author

Angiography-Derived Microvascular Resistance: Elegant Theory, Elusive Accuracy.

JACC. Cardiovascular interventions·2026
Same author

Direct-to-Participant Enrollment in a Virtual Trial: Lessons Learned From the Heartline Study.

JACC. Advances·2026
Same author

Role of the trigeminal system in pancreatic innervation: new concept and challenge - a narrative review.

Endocrine research·2026

Related Experiment Video

Updated: Apr 4, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
06:08

A Novel Method: Super-selective Adrenal Venous Sampling

Published on: September 15, 2017

24.6K

Pheochromocytoma Presenting as Partial HELLP Syndrome.

Yazan Daaboul1, Serge Korjian1, Lamis Khalil1

  • 1Lebanese American University Medical Center-Rizk Hospital, Gilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos, Lebanon.

Case Reports in Obstetrics and Gynecology
|September 10, 2015
PubMed
Summary

This case study highlights a rare instance of pheochromocytoma diagnosed alongside partial HELLP syndrome in a pregnant patient. Surgical removal of the adrenal tumor resolved hypertension and normalized lab values.

More Related Videos

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection
02:22

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Published on: April 12, 2024

1.1K
Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

1.8K

Related Experiment Videos

Last Updated: Apr 4, 2026

A Novel Method: Super-selective Adrenal Venous Sampling
06:08

A Novel Method: Super-selective Adrenal Venous Sampling

Published on: September 15, 2017

24.6K
Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection
02:22

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection

Published on: April 12, 2024

1.1K
Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

1.8K

Area of Science:

  • Obstetrics and Gynecology
  • Endocrinology
  • Cardiology

Background:

  • Partial HELLP syndrome (Hemolysis, Elevated Liver enzymes, Low Platelets) is a severe pregnancy complication.
  • Pheochromocytoma, a rare adrenal tumor causing hypertension, is seldom diagnosed during pregnancy, especially with concurrent HELLP syndrome.

Purpose of the Study:

  • To report an extremely rare case of pheochromocytoma co-occurring with partial HELLP syndrome in a pregnant patient.
  • To describe the diagnostic and management challenges in such a complex clinical scenario.

Main Methods:

  • Case report of a 25-year-old multigravida woman at 30 weeks gestation with partial HELLP syndrome.
  • Clinical presentation, pharmacologic management, urgent cesarean section, and postoperative work-up for secondary hypertension causes.

Main Results:

  • The patient presented with symptoms of partial HELLP syndrome unresponsive to medical therapy, necessitating an urgent cesarean section.
  • Postoperatively, persistent hypertension led to the diagnosis of a right adrenal pheochromocytoma.
  • Tumor resection resulted in complete resolution of symptoms and normalization of laboratory findings.

Conclusions:

  • Pheochromocytoma should be considered in the differential diagnosis of severe or refractory hypertension in pregnancy, even in the presence of HELLP syndrome.
  • Timely diagnosis and surgical management of pheochromocytoma can lead to favorable maternal and fetal outcomes.