Related Experiment Video

Updated: Apr 4, 2026

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
07:26

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides

Published on: November 21, 2013

13.5K

Self-assembly of α-helical polypeptides driven by complex coacervation

Dimitrios Priftis1, Lorraine Leon1, Ziyuan Song2

  • 1Institute for Molecular Engineering, University of Chicago, Chicago, IL 60637 (USA).

Angewandte Chemie (International Ed. in English)
|September 10, 2015
PubMed
Summary

Chiral polypeptides can self-assemble into liquid complexes, forming nanoscale coacervate-core micelles. This controlled assembly offers enhanced salt resistance and potential for delivering biological molecules.

Keywords:
chiralityhelical structuresmicellespeptidesself-assembly

More Related Videos

Detecting and Characterizing Protein Self-Assembly In Vivo by Flow Cytometry05:58

Detecting and Characterizing Protein Self-Assembly In Vivo by Flow Cytometry

Published on: July 17, 2019

11.6K
Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly09:34

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

8.1K

Related Concept Videos

Protein Complex Assembly02:41

Protein Complex Assembly

Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
17.1K
Protein Complex Assembly02:41

Protein Complex Assembly

2.7K
Protein Organization01:13

Protein Organization

Overview
161.9K
Protein Organization01:24

Protein Organization

Proteins are polymers of amino acid residues. They are versatile and responsible for different cellular functions, including DNA replication, molecular transport, catalysis, and structural support. Proteins have a hierarchical structure comprising at least three levels of organization: primary, secondary, and tertiary structure. Some large proteins have a quaternary structure where individual protein subunits are linked together.
The primary structure of a protein is its amino acid sequence....
10.0K
Protein Folding01:25

Protein Folding

Proteins are chains of amino acids linked together by peptide bonds. Upon synthesis, a protein folds into a three-dimensional conformation, critical to its biological function. Interactions between its constituent amino acids guide protein folding, and hence the protein structure is primarily dependent on its amino acid sequence.
Protein Structure Is Critical to Its Biological Function
Proteins perform a wide range of biological functions such as catalyzing chemical reactions, providing...
12.6K
Protein Folding01:22

Protein Folding

Overview
130.7K