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Discordance between ambulatory versus clinic blood pressure according to global cardiovascular risk group
Jinho Shin1, Sung Ha Park2, Ju Han Kim3
1Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Insights
Global cardiovascular risk influences blood pressure measurement discrepancies. Higher risk patients show less discordance between ambulatory and clinic readings, mainly due to lower white coat hypertension prevalence.
Area of Science:
- Cardiology
- Hypertension Management
- Diagnostic Accuracy
Background:
- Accurate hypertension diagnosis is crucial for effective management.
- Understanding discrepancies between ambulatory blood pressure (ABP) and clinic blood pressure (CBP) is key.
- The impact of global cardiovascular risk (GCR) on ABP/CBP discordance remains unclear.
Purpose of the Study:
- To investigate the relationship between GCR and discordance between ABP and CBP.
- To analyze the prevalence of white coat hypertension (WCH), treated normalized hypertension, and masked hypertension (MH) in relation to GCR.
Main Methods:
- Analysis of data from 1,916 subjects from the Korean Multicenter Registry for ABP monitoring.
- Classification of subjects based on diagnostic and therapeutic thresholds for CBP (140/90 mmHg) and ABP (135/85 mmHg).
- Assessment of GCR using European Society of Hypertension 2007 guidelines.
Main Results:
- Discordancy between ABP and CBP was higher in untreated (32.5%) versus treated (26.5%) patients.
- Prevalence of WCH/treated normalized hypertension was 14.4% and MH was 16.0%.
- Lower discordance between ABP and CBP was observed in the very high GCR group (OR, 0.649; p=0.003) and lower WCH/treated normalized hypertension prevalence (OR, 0.451; p<0.001).
Conclusions:
- ABP/CBP discordance is more common in untreated individuals.
- Higher global cardiovascular risk is associated with less ABP/CBP discordance.
- This association is primarily driven by a reduced prevalence of white coat hypertension in high-risk individuals.
Background/Aims:
The detection of white coat hypertension (WCH), treated normalized hypertension, and masked hypertension (MH) is important to improve the effectiveness of hypertension management. However, whether global cardiovascular risk (GCR) profile has any effect on the discordance between ambulatory blood pressure (ABP) and clinic blood pressure (CBP) is unknown.
Methods:
Data from 1,916 subjects, taken from the Korean Multicenter Registry for ABP monitoring, were grouped according to diagnostic and therapeutic thresholds for CBP and ABP (140/90 and 135/85 mmHg, respectively). GCR was assessed using European Society of Hypertension 2007 guidelines.
Results:
The mean subject age was 54.1 ± 14.9 years, and 48.9% of patients were female. The discordancy rate between ABP and CBP in the untreated and treated patients was 32.5% and 26.5%, respectively (p = 0.02). The prevalence of WCH or treated normalized hypertension and MH was 14.4% and 16.0%, respectively. Discordance between ABP and CBP was lower in the very high added-risk group compared to the moderate added-risk group (odds ratio [OR], 0.649; 95% confidence interval [CI], 0.487 to 0.863; p = 0.003). The prevalence of WCH or treated normalized hypertension was also lower in the very high added-risk group (OR, 0.451; 95% CI, 0.311 to 0.655).
Conclusions:
Discordance between ABP and CBP was observed more frequently in untreated subjects than in treated subjects, and less frequently in the very high added-risk group, which was due mainly to the lower prevalence of WCH or treated normalized hypertension.
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