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Dyspepsia in Ibadan
I O Olubuyide1, M A Atoba, E A Ayoola
1Department of Medicine, University College Hospital, Ibadan, Nigeria.
Tropical and Geographical Medicine
|October 1, 1989
Summary
Most dyspepsia cases in Ibadan present as non-ulcer dyspepsia, with endoscopy revealing no significant lesions in 55% of patients. Further research into dyspepsia causes is warranted.
Area of Science:
- Gastroenterology
- Internal Medicine
- Clinical Research
Background:
- Dyspepsia is a common gastrointestinal complaint.
- Understanding the underlying causes of dyspepsia is crucial for effective management.
- Previous studies have varied in their findings regarding the prevalence of organic causes in dyspeptic patients.
Purpose of the Study:
- To investigate the etiological spectrum of dyspepsia in patients presenting at a Nigerian tertiary hospital.
- To determine the prevalence of peptic ulcer disease and other endoscopic findings in dyspeptic patients.
- To assess the proportion of non-ulcer dyspepsia in this population.
Main Methods:
- Prospective study conducted from January 1982 to December 1986.
- Inclusion of 402 patients presenting with dyspepsia at the University College Hospital, Ibadan.
- Evaluation using upper gastro-intestinal fibre-optic endoscopy, laboratory, and radiological examinations.
Main Results:
- Analysis of 374 patients revealed peptic ulcers in 14% (duodenal ulcer 10.3%, gastric ulcer 3.7%).
- Mucosal inflammation of the esophagus and gastroduodenum was observed in 26.7% of patients.
- Endoscopic examination showed no significant lesions in 55% of the study participants, indicating non-ulcer dyspepsia.
Conclusions:
- The majority of dyspeptic patients in Ibadan exhibit non-ulcer dyspepsia.
- Endoscopic findings suggest a high prevalence of functional dyspepsia or other non-ulcerative causes.
- The pathogenesis of non-ulcer dyspepsia warrants further investigation in this demographic.