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Stir bar sorptive extraction applied to the analysis of biological fluids
Chrysoula Nazyropoulou1, Victoria Samanidou1
1Laboratory of Analytical Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Greece.
Abstract:
Stir bar sorptive extraction (SBSE) is a sample preparation technique, which is used for the extraction as well as the preconcentration of organic substances from various aqueous matrices, prior to the determination of the analytes with a separation technique, such as LC or GC, coupled to different detectors. Since 1999, when SBSE was first developed by Sandra and co-workers, SBSE has been used in the analysis of samples of environmental, food, pharmaceutical and biomedical origin. In this article, we focus on the application of SBSE in biological fluids.
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