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Onychomycosis Diagnosis and Management: Perspectives from a Joint Dermatology-Podiatry Roundtable
Abstract:
Onychomycosis prevalence is expected to rise as the population ages and the prevalence of diabetes, peripheral vascular disease, and other significant risk factors rise. Until recently, treatment options were limited due to safety concerns with oral antifungals and low efficacy with available topical agents. Efinaconzole and tavaborole were approved by the FDA in 2014 for onychomycosis treatment and provide additional effective topical treatment options for patients with mild-to-moderate disease. Dermatologists and podiatrists both regularly treat onychomycosis, yet there are striking differences between specialties in approach to diagnosis and treatment. In order to explore these differences a joint dermatology-podiatry roundtable of onychomycosis experts was convened. Although it has little effect on mycologic cure, debridement may be a valuable adjunct to oral or topical antifungal therapy, especially in patients with greater symptom burden. However, few dermatologists incorporate debridement into their treatment plans and referral to podiatry may be appropriate for some of these patients. Furthermore, podiatrists may be better equipped to manage patients with concurrent diabetes or peripheral vascular disease and elderly patients who are unable to maintain proper foot hygiene. Once cure is achieved, lifestyle and hygiene practices, maintenance/prophylactic onychomycosis treatment, and proactive tinea pedis treatment in patients and family members may help to maintain patients' cured status.
Insights
Onychomycosis, a fungal nail infection, is rising. New topical antifungals offer options, but debridement and podiatry referral may improve outcomes, especially for high-risk patients.
Area of Science:
- Dermatology and Podiatry
- Mycology
- Infectious Diseases
Background:
- Onychomycosis prevalence is increasing due to aging populations and rising rates of diabetes and peripheral vascular disease.
- Limited treatment options previously existed due to oral antifungal safety concerns and low topical efficacy.
- Recent FDA approvals of efinaconazole and tavaborole provide new topical treatments for mild-to-moderate onychomycosis.
Framework:
- A joint dermatology-podiatry expert roundtable convened to explore differences in onychomycosis diagnosis and treatment approaches.
- Discussion highlighted the role of debridement as an adjunct therapy, particularly for patients with significant symptoms.
- Specialty differences in incorporating debridement and managing high-risk patients (e.g., those with diabetes, PVD, or elderly) were noted.
Implementation:
- Debridement, while not directly impacting mycologic cure, can be a valuable addition to antifungal therapy.
- Referral to podiatry may be beneficial for dermatologists to manage debridement and complex patient cases.
- Podiatrists are well-suited to manage onychomycosis in patients with comorbidities like diabetes or PVD, and in elderly individuals requiring hygiene assistance.
Implications:
- Optimizing onychomycosis treatment requires understanding and bridging the gap between dermatological and podiatric approaches.
- Integrating debridement and leveraging podiatric expertise can enhance patient outcomes and symptom burden management.
- Post-cure strategies, including lifestyle changes, prophylactic treatment, and addressing tinea pedis in households, are crucial for sustained recovery.
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