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[Monofilaments in digestive system surgery].

F Bresadola, A Uzzau, R Menghi

    Annali Italiani Di Chirurgia
    |July 1, 1989
    PubMed
    Summary
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    New synthetic absorbable monofilament sutures, like polyglyconate, offer superior tensile strength and predictable reabsorption for gastrointestinal surgery. Clinical and experimental data support their use in digestive tract anastomoses.

    Area of Science:

    • Surgical Materials Science
    • Gastrointestinal Surgery
    • Biomaterials Engineering

    Background:

    • Synthetic absorbable sutures are crucial in modern surgery.
    • Comparing multifilament and monofilament sutures is essential for optimal tissue repair.
    • Understanding suture properties like tensile strength and reabsorption is key for clinical success.

    Purpose of the Study:

    • To compare multifilament and monofilament synthetic absorbable sutures.
    • To evaluate polyglyconate (a glycolic acid and trimethylene carbonate copolymer) for gastrointestinal surgery.
    • To assess the clinical and experimental efficacy of polyglyconate sutures.

    Main Methods:

    • Comparative analysis of suture properties: tensile strength, in vivo strength retention, reabsorbability, and capillarity.

    Related Experiment Videos

  • Clinical evaluation of 43 manual gastroenteric anastomoses using polyglyconate sutures with endoscopic follow-up.
  • Experimental study on 30 enteric anastomoses in rats, assessed via bacteriology, light microscopy, and electron microscopy.

    • Main Results:

    • Polyglyconate monofilament sutures demonstrated favorable theoretical properties for gastrointestinal surgery.
    • Clinical follow-up of gastroenteric anastomoses showed positive outcomes.
    • Experimental studies confirmed the theoretical properties of polyglyconate sutures in vivo.

    Conclusions:

    • Synthetic absorbable monofilament sutures, specifically polyglyconate, are recommended for gastrointestinal surgery.
    • Polyglyconate sutures exhibit predictable reabsorption via non-enzymatic hydrolysis over approximately 180 days.
    • Both clinical and experimental evidence supports the use of polyglyconate sutures in digestive surgery.