Related Experiment Video
Updated: Aug 17, 2026

Preparation and Characterization of Individual and Multi-drug Loaded Physically Entrapped Polymeric Micelles
Published on: August 28, 2015
In-vitro diffusion kinetics of salbutamol sulphate from microcapsules coated with Eudragit RS 100
Abstract:
Diffusion plays an important role in controlled release drug delivery system. Salbutamol sulphate, which is a bronchodilatory drug for asthma, was microencapsulated with a polyacrylic resin: Eudragit RS 100. Drug release data have been analyzed according to various release kinetics like Zero order, First order and Higuchi kinetics. Suice Higuchi mechanism seemed to predominate, the diffusivity rate constant (KBL) and the diffusion coefficient (Da) were estimated according to Baker-Lonsdale method at pH 1.2.
Related Concept Videos
Passive Diffusion: Overview and Kinetics
When administered orally, drugs establish a substantial concentration gradient between the gastrointestinal (GI) lumen and the bloodstream, expediting their diffusion into...
Factors Influencing Drug Absorption: Drug Dissolution
Methods for Studying Drug Absorption: In vitro
The diffusion cell method uses a two-compartment cell, including a donor compartment with the drug solution, which simulates the environment where the drug is applied, and a receptor compartment with a buffer solution, which simulates the environment...
In Vitro Drug Dissolution: Compendial Testing Models II
In Vitro Drug Dissolution: Alternative Methods
Modified-Release Drug Delivery Systems: Bioavailability

