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[An experience of using divasa in the treatment of cerebrovascular insufficiency]

E I Chukanova1, A N Bogolepova1, A S Chukanova1

  • 1Pirogov Russian National Research Medical University, Moscow.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|September 11, 2015
PubMed

Insights

Divasa effectively treats cerebrovascular insufficiency by reducing asthenic symptoms and improving quality of life. This study shows positive effects on patient well-being and safety.

Area of Science:

  • Neurology
  • Pharmacology

Background:

  • Cerebrovascular insufficiency can lead to debilitating symptoms such as asthenia, autonomic dysfunction, and vestibular/ataxic disorders.
  • Chronic cerebrovascular disease impacts patient quality of life and neurological function.

Purpose of the Study:

  • To evaluate the clinical efficacy and safety of divasa in treating patients with cerebrovascular insufficiency.
  • To assess the impact of divasa on asthenic, autonomic, vestibular, and ataxic symptoms.

Main Methods:

  • A study involving 40 patients with chronic cerebrovascular insufficiency treated with divasa.
  • Symptom severity assessed using Visual Analogue Scale (VAS), alongside neuropsychological and quality of life questionnaires (MMSE, MFI-20, HAM-A, SF-36).
  • Plasma levels of fibrinogen and von Willebrand factor were measured; a control group was included for comparison.

Main Results:

  • Divasa significantly reduced asthenic symptoms, anxiety, sleep disturbances, and autonomic disorders, improving patients' quality of life.
  • A notable decrease and normalization of plasma fibrinogen and von Willebrand factor levels were observed.
  • The drug was well-tolerated, with only 5% experiencing allergic reactions.

Conclusions:

  • Divasa demonstrated a positive effect on the condition of patients with cerebrovascular insufficiency.
  • The drug is recommended for inclusion in the comprehensive treatment of these patients.
  • Further research may explore long-term efficacy and specific mechanisms of action.
Abstract

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