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Chromosome aberrations and dominant lethals in Culex fatigans due to mercuric chloride
G P Sharma1, R C Sobti, A Chaudhry
1Department of Zoology, Panjab University, Chandigarh, India.
Abstract:
The mosquito, Culex fatigans, was used for determining the possible mutagenic potential of mercuric chloride, using chromosome aberrations and frequency of dominant lethals as the parameters. As many as 27.75 +/- 0.85% aberrations against 2.75 +/- 0.35% (P less than 0.001) in the controls were observed in the chromosomes of the animals treated with 0.001 microgram/ml of mercuric chloride. Similarly the frequency of dominant lethals was statistically significant in the treated lot. The results indicate that this compound is genotoxic.