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Updated: Apr 4, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
Published on: August 15, 2025
[Conservative and surgical treatment of patients with resistant epilepsy]
S A Gromov1, N E Ivanova2, V R Kasumov2
1Bekhterev St. Petersburg Psychoneurological Research Institute, St. Petersburg.
Aim:
To optimize drug treatment in early (6 months) and late (up to 3 years) stages of postoperative period and to study its efficacy.
Material And Methods:
There were selected 72 patients with resistant epilepsy and epileptic encephalopathy symptoms from 467 patients operated for epilepsy.
Results:
By the end of a 3-year follow-up observation, we found the reduction in seizure frequency and seizure control in 66.3% of patients; regression of EEG paroxysmal activity in 56.8% and reduction in mental disorder symptoms (anxiety and depression) in 12.7%.
Conclusion:
The data obtained substantiate the necessity to optimize antiepileptic and pathogenetic drug treatment of patients with resistant epilepsy and encephalopathy symptoms during the 3-year postoperative period.
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