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Psychostimulant prescribing trends in a paediatric population in Ireland: a national cohort study
Fiona Boland1, Rose Galvin2,3, Udo Reulbach4,5
1HRB Centre for Primary Care Research, Department of General Practice, Royal College of Surgeons in Ireland, 123 St Stephens Green, Dublin 2, Ireland. fionaboland@rcsi.ie.
Insights
Psychostimulant prescribing in Irish children and adolescents significantly increased from 2002 to 2011, with costs rising substantially. Further research is needed on combined psychotropic medication use in this demographic.
Area of Science:
- Pediatric pharmacology
- Public health surveillance
- Health economics
Background:
- International trends show rising psychotropic medication use in children.
- This study investigates psychotropic prescribing patterns in Irish youth.
Purpose of the Study:
- To examine the prevalence and secular trends of psychotropic prescribing in Irish children and adolescents.
- To analyze associated costs and concomitant medication use.
Main Methods:
- Utilized the Irish General Medical Services (GMS) pharmacy claims database (2002-2011).
- Calculated prescribing rates per 1000 population by age group and gender.
- Examined concomitant prescriptions and total expenditure on psychotropic medications.
Main Results:
- Psychostimulant prescriptions increased from 3.77 to 8.63 per 1000 population between 2002 and 2011.
- Methylphenidate was the most common psychostimulant; use was highest in 12-15 year olds.
- Total expenditure on these medications rose from €89,254 to €1,532,016.
Conclusions:
- Significant increase in psychostimulant prescribing rates and costs observed in Irish youth.
- Concomitant use of psycholeptics (8%) and antidepressants (2%) noted.
- Further research is essential to evaluate the safety, efficacy, and economic impact of combined psychotropic prescribing.
Background:
Psychotropic paediatric prescribing trends are increasing internationally. The aim of this study is to examine the prevalence and secular trends in psychotropic prescribing in Irish children and adolescents between 2002 and 2011.
Methods:
Data was obtained from the Irish General Medical Services (GMS) scheme pharmacy claims database from the Health Service Executive Primary Care Reimbursement Services (HSE-PCRS). Prescribing rates per 1000 eligible population and associated 95% confidence intervals (CIs) were calculated across years (2002-2011), age groups (0-4, 5-11, 12-15 years) and gender. Rates of concomitant prescriptions for psycholeptics and antidepressants were also examined. The total expenditure costs were calculated and expressed as a percentage of the cost of all prescriptions for this age group (≤ 15 years).
Results:
In 2002, 3.77/1000 GMS population (95% CI: 3.53-4.01) received at least one psychostimulant prescription and this rate increased to 8.63/1000 GMS population (95% CI: 8.34-8.92) in 2011. Methylphenidate was the most frequently prescribed psychostimulant. For both males and females the prevalence of medication use was highest among the 12-15 year old group. On average, a psycholeptic medication was prescribed to 8% of all psychostimulant users and an antidepressant was concomitantly prescribed on average to 2%. Total expenditure rose from €89,254 in 2002 to €1,532,016 in 2011.
Conclusions:
The rate and cost of psychostimulant prescribing among GMS children and adolescents in Ireland increased significantly between 2002 and 2011. Further research is necessary to assess the safety, efficacy and economic impact of concomitant psychotropic prescribing in this population.
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