Related Experiment Video

Updated: Apr 4, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.2K

Quantitative sinonasal symptom assessment in an unselected pediatric population with cystic fibrosis

Jennifer L Wentzel1, Isabel Virella-Lowell, Rodney J Schlosser

  • 1Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.

American Journal of Rhinology & Allergy
|September 12, 2015
PubMed

Insights

The Sinus and Nasal Quality of Life Survey (SN-5) effectively measures sinonasal symptoms in children with cystic fibrosis (CF). Scores correlate with sinusitis episodes and missed school days, aiding in symptom monitoring.

Area of Science:

  • Pediatric Otolaryngology
  • Pulmonology
  • Quality of Life Research

Background:

  • Cystic Fibrosis (CF) often impacts sinonasal health in pediatric patients.
  • Establishing baseline sinonasal quality of life (QoL) is crucial for understanding disease burden.
  • Current QoL metrics need validation in unselected pediatric CF populations.

Purpose of the Study:

  • To determine baseline sinonasal QoL scores in children with CF.
  • To assess the correlation between sinonasal QoL scores and clinical outcomes.
  • To evaluate the utility of the Sinus and Nasal Quality of Life Survey (SN-5) tool.

Main Methods:

  • Utilized the SN-5 tool in 50 pediatric CF patients (ages 2-12).
  • Collected data on sinusitis episodes, antibiotic use, hospitalizations, and school absenteeism.
  • Reviewed CF genotype, pulmonary function, sinus surgery history, and CT scan results.

Main Results:

  • Pediatric CF patients had lower average SN-5 scores than reported for chronic sinusitis.
  • SN-5 scores correlated significantly with sinusitis episodes, antibiotic prescriptions, and missed school days.
  • No significant correlation found between SN-5 scores and CF genotype, pulmonary function, or hospitalizations.

Conclusions:

  • The SN-5 tool is a reliable and safe method for monitoring sinonasal symptoms in pediatric CF patients.
  • SN-5 scores provide valuable insights into the impact of sinonasal issues on daily life.
  • This tool can aid clinicians in managing sinonasal health in this population.
Abstract

More Related Videos

Nasal Potential Difference to Quantify Trans-epithelial Ion Transport in Mice08:55

Nasal Potential Difference to Quantify Trans-epithelial Ion Transport in Mice

Published on: July 4, 2018

8.3K
Standardized Measurement of Nasal Membrane Transepithelial Potential Difference NPD09:47

Standardized Measurement of Nasal Membrane Transepithelial Potential Difference NPD

Published on: September 13, 2018

17.5K

Related Concept Videos

Physical Assessment of the Respiratory Tract I: Health History01:28

Physical Assessment of the Respiratory Tract I: Health History

Physical assessment of the respiratory tract is critical to patient care. It allows healthcare professionals to identify and manage various respiratory conditions. The process involves a combination of subjective and objective data collection.
Subjective Data
Subjective data provides vital information about the patient's health history and symptoms. This data is typically collected through interviews in which patients describe their experiences, symptoms, and concerns.
Health history and...
1.2K
Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
620
Cystic Fibrosis: Pathogenesis01:23

Cystic Fibrosis: Pathogenesis

Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
1.1K
Physical Assessment of the Respiratory Tract II: Inspection01:27

Physical Assessment of the Respiratory Tract II: Inspection

Physical assessment of the respiratory tract through inspection is a crucial step in understanding the patient's respiratory health. It provides insights into the functioning of the respiratory system, the musculoskeletal structure, and even the patient's nutritional status. This comprehensive approach involves observing several vital aspects: chest configuration, breathing patterns, respiratory rates, skin color, and use of accessory muscles.
Chest Configuration
The chest configuration...
1.2K
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
3.4K
Suctioning the Nasopharyngeal Airway01:29

Suctioning the Nasopharyngeal Airway

Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
5.4K