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Isolation and partial characterization of a novel form of low molecular weight kininogen from guinea pig plasma
K Yoshida1, A Saito, H Sinohara
1Department of Biochemistry, Kinki University School of Medicine, Osaka, Japan.
Biochemistry International
|December 1, 1989
Abstract:
Two kinds of low molecular weight kininogen (termed LK1 and LK2) were isolated from pooled plasma of guinea pigs. When polyclonal antisera raised against the individual proteins were used, immunological cross-reactions were observed between LK1 and high molecular weight kininogen (HK), but not either between LK1 and LK2 or between LK2 and HK. After tissue injury, plasma level of LK1 doubled while those of LK2 and HK remained relatively unchanged.