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State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
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Prenatal Brain Imaging in Isolated vs. Complicated Club Foot: A Cohort Study
I Gat1, O Bar Yosef2, C Hoffmann3
1Antenatal Diagnostic Unit, Department of Obstetrics and Gynecology, Sheba Medical Center, Tel HaShomer, Ramat Gan, Israel, affiliated with the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Ultraschall in Der Medizin (Stuttgart, Germany : 1980)
|September 12, 2015
Summary
Fetal brain MRI is valuable for complex talipes equinovarus (TEV) cases, revealing more abnormalities than ultrasound. Its benefit in isolated TEV requires further study.
Area of Science:
- Medical Imaging
- Fetal Medicine
- Neurology
Background:
- Talipes equinovarus (TEV) is a common congenital anomaly.
- Differentiating isolated from complex TEV is crucial for prognosis and management.
- Complex TEV is associated with poorer neurological outcomes, necessitating fetal brain evaluation.
Purpose of the Study:
- To assess the utility of fetal brain magnetic resonance imaging (MRI) in evaluating fetuses with TEV.
- To compare the diagnostic yield of fetal brain MRI with ultrasound (US) in TEV cases.
- To determine the contribution of fetal brain MRI to antenatal diagnosis and management.
Main Methods:
- Retrospective review of pregnant patients referred for fetal brain MRI due to TEV.
- Classification of TEV into isolated and complex based on associated anomalies.
- Comparison of brain US findings with fetal brain MRI results.
- Analysis of diagnostic discrepancies between US and MRI.
Main Results:
- Fetal brain MRI identified additional pathologies in 57.1% of complex TEV cases, compared to 28.6% with US.
- MRI revealed abnormalities not detected by US in 6 cases of complex TEV.
- In isolated TEV cases, both US and MRI were largely normal, with limited added value from MRI.
Conclusions:
- Fetal brain MRI is an effective tool for antenatal evaluation of complicated TEV, detecting more anomalies than US.
- The role of fetal brain MRI in isolated TEV cases is less clear and warrants further investigation.
- Fetal brain MRI is relevant for evaluating non-central nervous system (CNS) anomalies associated with TEV.
