[Plasma CK-MB activity and QRS score in estimating acute myocardial infarct size]

Comparison of the peak value of plasma isoenzyme MB of creatine kinase (CK-MB) and the modified Selvester QRS score system from the standard 12-lead electrocardiogram in estimating acute myocardial infarct size and predicting hospital prognosis was performed in 52 patients with initial acute myocardial infarction (AMI). A correlation coefficient (C.C.) of 0.51 in all these patients was found. The C.C. in the patients with anterior AMI (n = 22, r = 0.64) is larger than that in inferior AMI (n = 30, r = 0.34). The prognostic value of the two methods are different. Peak CK-MB activity could predict hospital mortality and morbidity (serious arrhythmia or/and Killip AMI classification more than class III) for both anterior and inferior AMI; however, the QRS score system was significant only for anterior AMI. The clinical significance of a high ratio of peak CK-MB activity to QRS score was discussed briefly.