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A Gompertz age-specific mortality rate model of aging: modification by dietary restriction in rats
P J Neafsey1, H Boxenbaum, D A Ciraulo
1Tufts University School of Medicine, Boston, Massachusetts.
Drug Metabolism Reviews
|January 1, 1989
Abstract:
A Gompertz age-specific mortality rate model characterizing actuarial effects of food restriction in rats was developed based on mortality data from the study of Yu et al. (J. Gerontol. 40: 657-670, 1985). Results indicated that in the presence of adequate nutrition, food restriction reduces the aging rate parameter in a consistent manner, regardless of the age at which food restriction is initiated.