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Updated: Apr 4, 2026
Treatment of Osteochondral Defects in the Rabbit's Knee Joint by Implantation of Allogeneic Mesenchymal Stem Cells in Fibrin Clots
Published on: May 21, 2013
Dysplasia Epiphysealis Hemimelica Treated with Osteochondral Allograft: A Case Report
Chris A Anthony1, Brian R Wolf1
1The Department of Orthopaedic Surgery and Rehabilitation, University of Iowa Hospitals and Clinics , 200 Hawkins Drive, 01008 JPP, Iowa City, IA 52242 , USA.
Background:
Dysplasia epiphysealis hemimelica (DEH), or Trevor's disease, is a developmental disorder of the pediatric skeleton characterized by asymmetric osteochondral overgrowth.
Methods:
We present the case of a five year old boy with a two year history of right knee pain and evidence of DEH on imaging who underwent initial arthroscopic resection of his lesion with subsequent recurrence. The patient then underwent osteochondral allograft revision surgery and was asymptomatic at two year follow-up with a congruent joint surface.
Results:
To our knowledge, this is the first reported case of a DEH lesion treated with osteochondral allograft and also the youngest reported case of osteochondral allograft placement in the literature.
Conclusions:
Osteochondral allograft may be a viable option in DEH and other deformities of the pediatric knee.
Level Of Evidence:
Level V.
