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Lateral Epicondylitis and Tobacco Use: A Case-Control Study.
Avery E Michienzi1, Christopher P Anderson2, Sandy Vang1
1Department of Orthopaedic Surgery, University of Minnesota , Minneapolis, MN ; Department of Orthopaedics, Regions Hospital , St. Paul, MN.
The Iowa Orthopaedic Journal
|September 12, 2015
Summary
Former smokers had a significantly higher incidence of lateral epicondylitis (LE). This study suggests a link between smoking history and developing this common tendinopathy, warranting further investigation.
Area of Science:
- Orthopedics
- Epidemiology
- Public Health
Background:
- Lateral epicondylitis (LE) is a prevalent tendinopathy with poorly understood etiology.
- Tobacco use is a potential risk factor implicated in various tendinopathies.
Purpose of the Study:
- To investigate the association between tobacco use and the incidence of lateral epicondylitis.
- To determine if smoking status is a risk factor for developing LE.
Main Methods:
- Retrospective cohort study design.
- Adult patients diagnosed with LE were matched with control patients exhibiting other upper extremity conditions based on age, gender, and occupation.
- Comparison of smoking incidence between LE and control groups (65 cases, 217 controls).
Main Results:
- Former smokers showed a statistically significant higher odds of having LE (2.28 times higher) compared to controls.
- Current smokers and former smokers combined had higher, though not statistically significant, odds of LE (1.45 times higher).
- 46.2% of LE patients were non-smokers, 35.4% former smokers, and 18.5% current smokers.
Conclusions:
- A significant association exists between being a former smoker and developing lateral epicondylitis.
- The findings suggest a potential relationship between smoking history and LE incidence.
- Further research is recommended to elucidate the precise nature of the smoking-LE relationship.

