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Advances and needs for endotoxin-free production strains

Seiichi Taguchi1,2, Toshihiko Ooi3,4, Kouhei Mizuno5

  • 1Division of Applied Chemistry, Graduate School of Engineering, Hokkaido University, N13-W8, Kita-ku, Sapporo, 060-8628, Japan. staguchi@eng.hokudai.ac.jp.

Applied Microbiology and Biotechnology
|September 13, 2015
PubMed
Summary

Gram-positive bacteria like Bacillus and yeasts offer safe, endotoxin-free platforms for producing valuable products such as bioplastics and proteins. These microbes are ideal for sustainable industrial applications, avoiding the immunostimulatory lipopolysaccharide (LPS) found in Gram-negative hosts.

Keywords:
BacteriocinsFood-grade Gram-positive bacteriaLipopolysaccharideMembrane proteinsPolyhydroxyalkanoatesYeasts

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