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Related Concept Videos

Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Drug Dosing: Geriatric Patients01:15

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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The Effect of Aging on Tissues01:19

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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Aging01:26

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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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Related Experiment Video

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Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
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[Pleasure and aging in the elderly].

Philippe Denormandie1, Stéphane Sanchez2, Stéphane Hugon3

  • 1Institut du Bien Vieillir Korian, 32 rue Guersant, 75017 Paris, France.

Soins. Gerontologie
|September 15, 2015
PubMed
Summary

Older adults aged 65+ were surveyed about their relationship with pleasure and aging. Findings reveal insights into senior enjoyment and potential self-censorship regarding pleasure in later life.

Keywords:
ageingelderly personfamillefamilypersonne âgéeplaisirpleasurevieillissement

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Area of Science:

  • Gerontology
  • Sociology of Aging
  • Psychology of Aging

Context:

  • Investigates the evolving relationship between pleasure and aging in individuals 65 and older.
  • Explores perceptions of pleasure and enjoyment among senior citizens.
  • Compares the views of older adults (65+) with a younger demographic (15-64) on aging and pleasure.

Purpose:

  • To clarify the older population's connection with pleasure as they age.
  • To determine if older adults experience self-censorship regarding pleasure or embrace life fully.
  • To understand how younger individuals perceive seniors' capacity for pleasure and enjoyment.

Summary:

  • A survey of individuals aged 65 and over explored their feelings about pleasure in aging, including the ways they find enjoyment and potential self-censorship.
  • A comparative survey of individuals aged 15-64 assessed their perceptions of older adults' enjoyment and how seniors engage with life.
  • The research examines whether older adults continue to find pleasure and how they express it, contrasting with younger perspectives.

Impact:

  • Provides a nuanced understanding of pleasure and aging, challenging stereotypes about senior life.
  • Informs social gerontology and psychological studies on well-being in later life.
  • Offers insights for developing age-inclusive approaches to leisure and quality of life for older adults.