Related Experiment Video

Updated: Apr 4, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

15.7K

Temporal trends and factors associated with pediatric hospitalizations with respiratory infection

Yingxue Chen1, Jianfang Liu2, Elaine Larson1,2

  • 1a Department of Epidemiology , Columbia University Mailman School of Public Health , New York , NY , USA and.

The Journal of Asthma : Official Journal of the Association for the Care of Asthma
|September 15, 2015
PubMed

Insights

Asthma significantly increases children's risk of hospitalization for respiratory infections. The study found a rising prevalence of asthma among these pediatric patients over a seven-year period.

Area of Science:

  • Pediatric emergency medicine
  • Respiratory health
  • Epidemiology

Background:

  • Asthma is a major cause of pediatric emergency room visits.
  • Children with asthma face severe respiratory infection outcomes.
  • Understanding asthma's impact on pediatric respiratory infections is crucial.

Purpose of the Study:

  • Compare hospitalized children with and without respiratory infections.
  • Analyze trends in asthma prevalence among children hospitalized with respiratory infections in NYC (2006-2012).
  • Determine asthma's effect on hospital stay duration for pediatric respiratory infection cases.

Main Methods:

  • Historical prospective study design.
  • Utilized electronic health records and billing codes from a large pediatric hospital (2006-2012).
  • Analyzed 83,348 patient discharges, focusing on respiratory infections and asthma comorbidities.

Main Results:

  • Asthma (OR 4.68) was a significant risk factor for pediatric hospitalization with respiratory infection.
  • The proportion of asthma among children hospitalized with respiratory infection rose from 19.2% to 28.2% (2006-2012).
  • Asthma patients had shorter hospital stays (5.3 days) compared to non-asthma patients (9.0 days).

Conclusions:

  • Asthma is a key risk factor for pediatric hospitalization due to respiratory infections.
  • The prevalence of asthma among hospitalized children with respiratory infections is increasing in urban settings.
  • Early identification and management of asthma may reduce severe respiratory infection outcomes in children.
Abstract

Keywords:
Acute bronchitis and bronchiolitisasthmahuman metapneumovirusinfluenzapneumoniarespiratory syncytial virusrhinovirus

More Related Videos

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection09:01

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection

Published on: December 10, 2013

8.5K

Related Concept Videos

Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
1.3K
Influenza01:27

Influenza

Influenza is an acute, highly communicable viral disease that affects the respiratory tract and is responsible for seasonal epidemics worldwide. Influenza A is the most prevalent type associated with widespread outbreaks and is subtyped based on two surface glycoproteins: hemagglutinin (H) and neuraminidase (N), as in H1N1. These glycoproteins are essential for viral infectivity, transmission, and immune recognition. Transmission occurs primarily through respiratory droplets and contaminated...
42
Common Respiratory Disorders01:31

Common Respiratory Disorders

Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
1.8K
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
1.2K
Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more...
36
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
4.9K