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Genome-wide association study of growth traits in Jinghai Yellow chicken hens using SLAF-seq technology
W H Wang1,2,3, J Y Wang1,2, T Zhang1,2
1College of Animal Science and Technology, Yangzhou University, Jiangsu Yangzhou, 225009, China.
Abstract:
In this study, we performed a new genome-wide association study using SLAF-seq technology. A total of 19 single nucleotide polymorphism effects involving nine different SNP markers reached 5% Bonferroni-corrected genome-wide significance. In addition, a 5-Mb region spanning 72.9-77.9 Mb on GGA4, exhibiting many significant SNP effects, was identified. The LDB2 gene in this region had a very strong association with body weight. Another SNP on GGA1, located in the INTS6 gene, had the strongest association with late body weight (weeks 10-16). Some of the SNPs that reached suggestive significance level overlapped with previously reported quantitative trait locus regions.
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