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MicroRNAs Regulating Signaling Pathways: Potential Biomarkers in Systemic Sclerosis

Yisha Li1, Jing Huang1, Muyao Guo1

  • 1Department of Rheumatology, Xiangya Hospital, Central South University, Changsha 410008, China.

Genomics, Proteomics & Bioinformatics
|September 15, 2015
PubMed
Summary

MicroRNAs (miRNAs) are epigenetic regulators in systemic sclerosis (SSc), a fibrotic autoimmune disease. This review highlights their role in TGF-β signaling, offering potential for new SSc biomarkers and treatments.

Keywords:
MicroRNAMicrovascular endothelial cellSignaling pathwaySystemic sclerosisTGF-βToll-like receptor

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