Related Experiment Video
Updated: Apr 4, 2026

Handling of the Cotton Rat in Studies for the Pre-clinical Evaluation of Oncolytic Viruses
Published on: November 24, 2014
Characterization of a novel full-length bovine endogenous retrovirus, BERV-β1
Claudia Torresi1, Cristina Casciari1, Monica Giammarioli1
1Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche, via Salvemini 1, 06126, Perugia, Italy.
Abstract:
Recent studies have suggested that certain classes of endogenous retroviruses (ERVs) may be present in cattle. The aim of this study was increase the scope of knowledge regarding bovine ERVs. The ovine ERV β1 pro/pol sequence was used to design a primer set for polymerase chain reaction (PCR) amplification of a similar sequence in the bovine genome. Through phylogenetic and bioinformatic analysis of the PCR product sequence together with its flanking region, a sequence 8107 bp in length was characterized. This sequence had a typical 5'-LTR-gag-pro-pol-env-LTR-3' organization, and phylogenetic investigation defined it as a bovine ERV β1. Thus, we were able to identify a novel bovine endogenous retrovirus element.
Related Concept Videos
Retrovirus Life Cycles
Retroviruses
Non-LTR Retrotransposons
Leaky Scanning
LTR Retrotransposons
The internal coding region of LTR retrotransposons and their mechanism of transposition closely resembles a...
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

