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Related Concept Videos

COPD: Management Using Bronchodilators and Corticosteroids01:26

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Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
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Antiasthma Drugs: β2-Adrenoceptor Agonists01:25

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Bronchodilators are critical in managing asthma, a chronic respiratory condition characterized by airway constriction due to inflammation and hyper-reactivity. Specifically, bronchodilators ease this constriction by relaxing the bronchial muscles, facilitating easier breathing.
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce...
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Inhaled Medications01:23

Inhaled Medications

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Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
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Drugs Used in Lower Respiratory Disorders: Overview01:17

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Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
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Chronic Obstructive Pulmonary Disease-V: Management01:29

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Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
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Chronic Obstructive Pulmonary Disease01:24

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COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
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Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System
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Bronchodilators use in patients with COPD.

Yaa-Hui Dong1, Chia-Lin Hsu2, Ying-Ying Li3

  • 1Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA ; Center of Comparative Effectiveness Research, National Center of Excellence for Clinical Trial and Research, National Taiwan University Hospital, Taipei, Taiwan.

International Journal of Chronic Obstructive Pulmonary Disease
|September 15, 2015
PubMed
Summary

This study found excessive use of oral and short-acting bronchodilators in COPD management. Optimizing inhaled treatments and reducing oral bronchodilator prescriptions are recommended for better patient care.

Keywords:
bronchodilatorschronic obstructive pulmonary diseaseprescribing patterns Taiwan

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Area of Science:

  • Pulmonology
  • Pharmacology
  • Health Services Research

Background:

  • Bronchodilators are essential for managing Chronic Obstructive Pulmonary Disease (COPD).
  • Understanding current bronchodilator prescribing patterns is crucial for optimizing COPD treatment.

Purpose of the Study:

  • To analyze bronchodilator prescribing patterns in COPD patients.
  • To evaluate trends over time, by physician specialty, and hospital level.

Main Methods:

  • Retrospective cohort study using Taiwan National Health Insurance Research Database (2001-2010).
  • Analysis of 21,235 bronchodilator prescriptions from 4,387 COPD patients.
  • Classification of prescriptions by medication class (oral/inhaled) and regimen (e.g., short-acting/long-acting).

Main Results:

  • Oral bronchodilators (xanthines, beta-2 agonists) dominated prescriptions (>60%), with nearly 80% being oral-alone regimens.
  • Inhaled bronchodilators accounted for less than 10% of prescriptions.
  • Oral bronchodilator use declined over time and varied by provider, with higher use by non-chest specialists and in primary care.

Conclusions:

  • Current prescribing practices show overuse of oral and short-acting bronchodilators in COPD.
  • There is a need for improved education and research to promote optimal inhaled bronchodilator use and reduce reliance on oral agents.