Adenoma Malignum Presenting With Profound Hyponatremia

Area of Science:

• Gynecologic Oncology
• Endocrinology

Background:

• Adenoma malignum, also known as minimal deviation adenocarcinoma, is a rare cervical cancer.
• Previous literature has documented mucinous vaginal discharge as a symptom.

Observation:

• A 52-year-old woman presented with substantial watery vaginal discharge.
• The patient also exhibited profound hyponatremia, indicating significant fluid and electrolyte imbalance.

Findings:

• This case highlights a previously unreported presentation of adenoma malignum with profound hyponatremia.
• The watery vaginal discharge was attributed to fluid losses associated with the tumor.

Implications:

• Adenoma malignum should be included in the differential diagnosis for patients presenting with watery vaginal discharge.
• This rare cervical malignancy can manifest with severe electrolyte disturbances, necessitating prompt recognition and management.