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Fabrication of Refractive-index-matched Devices for Biomedical Microfluidics
Published on: September 10, 2018
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On-chip integrated differential optical microring refractive index sensing platform based on a laminar flow scheme
Optics Letters
|September 15, 2015
Summary
This study introduces an integrated optical microring sensor for precise refractive index measurement. The differential design enhances reliability by minimizing environmental interference, enabling sensitive detection.
Area of Science:
- Photonics
- Microfluidics
- Sensing Technology
Background:
- Refractive index sensing is crucial for various applications.
- Environmental disturbances can impact sensor accuracy.
- Differential sensing approaches offer improved reliability.
Purpose of the Study:
- To develop an on-chip integrated differential optical microring sensor.
- To leverage laminar flow conditions for enhanced sensing.
- To achieve reliable and sensitive refractive index measurements.
Main Methods:
- Utilized an on-chip integrated differential optical microring resonator.
- Employed a shared microfluidic channel for sensing and reference resonators.
- Operated under laminar flow conditions to mitigate environmental disturbances.
Main Results:
- Achieved a noise floor of 80.0 MHz (0.3 pm).
- Demonstrated a bulk refractive index sensitivity of 17.0 THz/RIU (64.2 nm/RIU).
- Obtained a limit of detection of 1.4×10(-5) RIU within a 30-minute window and an 8°C range.
Conclusions:
- The proposed platform offers reliable and sensitive refractive index sensing.
- Close spacing and shared microfluidic channels effectively compensate for environmental fluctuations.
- The integrated design shows significant potential for advanced biosensing and chemical analysis.

