Related Experiment Video
Updated: Apr 3, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
Published on: September 5, 2017
Pyogenic Granuloma: A Retrospective 10-year Analysis of 82 Cases
Tadashi Akamatsu1, Ushio Hanai, Megumi Kobayashi
1Department of Plastic Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259-113, Japan. akamatu@is.icc.u-tokai.ac.jp.
Objective:
Pyogenic granuloma (PG) is a common acquired hemorrhagic benign vascular lesion of the skin and mucous membranes. Recently, PG was considered a capillary hemangioma and was renamed as lobular capillary hemangioma (LCH). A clinical retrospective analysis of PG cases in our institute over a period of 10 years was performed.
Methods:
The study involved 82 cases of pathologically diagnosed PG managed and treated at the Plastic Surgery Department of Tokai University between 1995 and 2004. Individual data from charts were reviewed for age, gender, affected site, size of lesion, predisposing factors, and treatment. All lesions were treated surgically using an excision followed by suture, or shave excision followed by CO2 laser ablation.
Results:
The overall male to female ratio was 1.5:1. In 28% of the total cases, a preceding lesion was evident prior to the occurrence of PG. The head and neck area were the most commonly affected sites (56%), followed by the upper limb (22%), trunk (16%), and lower limbs (6%). CO2 laser ablation was performed successfully in 24% of patients and resulted in no recurrences.
Conclusion:
Based on our results, we recommend surgical excision followed by CO2 laser ablation as the first-choice treatment for PGs.
Insights
Surgical excision followed by CO2 laser ablation is recommended for treating pyogenic granuloma (PG), a common vascular lesion. This combined approach demonstrated successful outcomes with no recurrences in a 10-year retrospective study.
Area of Science:
- Dermatology
- Plastic Surgery
- Vascular Lesions
Background:
- Pyogenic granuloma (PG), also known as lobular capillary hemangioma (LCH), is a frequent benign vascular tumor affecting skin and mucous membranes.
- Understanding the clinical characteristics and treatment efficacy of PG is crucial for effective patient management.
Purpose of the Study:
- To conduct a retrospective analysis of pyogenic granuloma cases over a 10-year period.
- To evaluate the effectiveness of different surgical treatments for PG.
Main Methods:
- Analysis of 82 pathologically diagnosed PG cases treated at Tokai University's Plastic Surgery Department (1995-2004).
- Review of patient data including age, gender, affected site, lesion size, predisposing factors, and treatment modalities.
- Surgical treatments included excision with suture or shave excision with CO2 laser ablation.
Main Results:
- The male to female ratio was 1.5:1.
- Head and neck (56%) were the most common sites, followed by upper limb (22%).
- CO2 laser ablation after shave excision was successful in 24% of cases with no reported recurrences.
Conclusions:
- Surgical excision followed by CO2 laser ablation is proposed as the preferred treatment for pyogenic granulomas.
- This combined therapeutic approach offers a promising strategy for managing PG with high success rates.
More Related Videos
03:47A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
Published on: October 25, 2024
07:42A Novel Microdissection Approach to Recovering Mycobacterium tuberculosis Specific Transcripts from Formalin Fixed Paraffin Embedded Lung Granulomas
Published on: June 5, 2014
Related Concept Videos
Acute Pyelonephritis II: Diagnostic Studies and Management
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...