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[Analgosedation as an adjuvant during surgery under local anesthesia]
Deutsche Zeitschrift Fur Mund-, Kiefer- Und Gesichts-Chirurgie
|July 1, 1989
Summary
Midazolam combined with Pentazocine or Piritramid provides safe and effective analgosedation for oral surgery. These intravenous medications are suitable adjuvants for local anesthesia, showing no significant adverse effects on respiration or circulation.
Area of Science:
- Anesthesiology
- Pharmacology
Background:
- Local anesthesia in oral surgery can be enhanced with adjunctive medications.
- Sedation and analgesia are crucial for patient comfort during invasive dental procedures.
Purpose of the Study:
- To evaluate the efficacy and safety of Midazolam for analgosedation during oral surgery.
- To assess Pentazocine and Piritramid as intravenous adjuvants to local anesthesia.
Main Methods:
- Twelve systemically healthy patients (ASA risk groups 1-2) undergoing oral surgery were included.
- Patients received intravenous Midazolam for sedation and either Pentazocine or Piritramid for analgesia.
- Local anesthesia was administered to all participants.
Main Results:
- Midazolam demonstrated suitability as a short-acting benzodiazepine for analgosedation.
- Neither Pentazocine nor Piritramid caused clinically relevant respiratory or circulatory depression.
- No major sleepiness was observed in patients receiving these medications.
Conclusions:
- Intravenous Midazolam, Pentazocine, and Piritramid are effective and safe adjuncts for local anesthesia in oral surgery.
- These agents facilitate analgosedation without compromising vital signs or causing excessive sedation.