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Exposure of rats and hamsters to sidestream smoke from cigarettes in a subchronic inhalation study
L von Meyerinck1, G Scherer, F Adlkofer
1Forschungsgesellschaft Rauchen und Gesundheit mbH, Hamburg, FRG.
Abstract:
A 90-day feasibility study was performed in which rats and hamsters were exposed to the sidestream smoke of cigarettes. The only histopathological changes observed were hyperplasia and metaplasia of the epithelium covering the dorsal nasal turbinate bones in rats. These effects were reversible within 90 days.