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Related Concept Videos

Teeth01:15

Teeth

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The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
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Tooth Anatomy01:21

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The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
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The Oral Microbiota01:27

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The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
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Development of the Oral Microbiota01:28

Development of the Oral Microbiota

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The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...
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Tonsillitis II: Management01:26

Tonsillitis II: Management

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This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.
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Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
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Flexural strength and mode of failure of interim implant-supported fixed dental prostheses following different conversion techniques and structural reinforcement.

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Updated: Apr 3, 2026

Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness
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Complete Edentulism and Comorbid Diseases: An Update.

David A Felton1

  • 1Department of Restorative Dentistry, West Virginia University School of Dentistry, Morgantown, WV.

Journal of Prosthodontics : Official Journal of the American College of Prosthodontists
|September 16, 2015
PubMed
Summary
This summary is machine-generated.

Complete edentulism, the loss of all teeth, is linked to various health issues. Research since 2008 explores connections between tooth loss and conditions like cardiovascular disease, obesity, and mortality.

Keywords:
COPDComplete edentulismcancercardiovascular diseasecomorbid diseasedementiamalnutritionmortalityobesitypneumoniarheumatoid arthritis

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Area of Science:

  • Oral Health and Systemic Disease Epidemiology
  • Public Health and Dental Research

Background:

  • The link between complete edentulism and systemic diseases was first noted in 2009.
  • Previous studies indicated associations but could not establish causality between tooth loss and comorbid conditions.

Purpose of the Study:

  • To provide an updated review of research published since 2008 on the relationship between complete edentulism and comorbid diseases.
  • To consolidate findings on the association between tooth loss and various systemic health outcomes.

Main Methods:

  • Systematic literature review of articles published from 2008 onwards.
  • Analysis of studies investigating the connection between complete edentulism and specific comorbid conditions.

Main Results:

  • Complete edentulism is associated with increased risks of malnutrition, obesity, cardiovascular disease, rheumatoid arthritis, pulmonary diseases (including COPD), and cancer.
  • A significant correlation exists between complete tooth loss and higher mortality rates.

Conclusions:

  • Complete edentulism is a significant indicator of potential systemic health problems.
  • Further research is warranted to understand the causal pathways between oral health and systemic disease incidence.