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Updated: Apr 3, 2026

Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Fiberoptic examination of swallowing in the breastfeeding infant
Susan Willette1, Laura Hinkes Molinaro1, Dana M Thompson2,3
1Department of Speech Pathology, Ann & Robert H. Lurie Children's Hospital of Chicago.
Insights
Fiberoptic endoscopic evaluation of swallowing (FEES) is a safe and effective tool for assessing swallowing difficulties in infants. This instrumental exam helps identify dysphagia in breastfeeding infants when other methods are unavailable.
Area of Science:
- Pediatric Medicine
- Otolaryngology
- Gastroenterology
Background:
- Fiberoptic endoscopic evaluation of swallowing (FEES) is the sole instrumental method for assessing swallowing in breastfeeding infants.
- Limited data exists on the efficacy and safety of FEES in this specific pediatric population.
Purpose of the Study:
- To analyze the indications for, findings of, and safety of FEES in breastfeeding infants.
- To evaluate the utility of FEES in diagnosing dysphagia in infants.
Main Methods:
- A case series design was employed, reviewing 24 FEES exams on 23 infants (10 months or younger).
- Data collected included indications for FEES, observed swallowing function, and any procedure-related complications.
Main Results:
- Common indications included feeding difficulties (52%), noisy breathing (28%), and cyanosis (16%).
- Dysphagia was prevalent, with laryngeal penetration (83%) and aspiration (50%) noted. Findings included laryngeal edema (29%).
- No immediate complications or adverse events were associated with the FEES procedure.
Conclusions:
- FEES is a safe and effective instrumental examination for evaluating swallowing in breastfeeding infants.
- It provides crucial diagnostic information for dysphagia in infants where no alternative instrumental assessments exist.
Objectives/Hypothesis:
Fiberoptic endoscopic evaluation of swallowing (FEES) is the only instrumental exam that can be used to assess swallowing in a breastfeeding infant. There is minimal data on its efficacy and safety in this patient population. Analyze the common indications for, findings of, and safety of FEES exam in breastfeeding infants.
Study Design:
Case series.
Methods:
Consecutive 10 months old or younger breastfed infants undergoing a FEES exam between June 1, 2012, and August 1, 2014, at a university-based, tertiary care urban children's hospital were studied. Common indications for and findings of FEES, as well as complications of the procedure, were determined.
Results:
Twenty-four FEES were reviewed on 23 patients. There were 14 males (58%). The average age was 14 weeks, and two children were premature. Common indications for FEES were feeding difficulties (52%), noisy breathing with/without feeding (28%), and cyanosis (16%). Of the patients who participated in active breastfeeding during the exam, a functional swallow was identified in 12.5%. The remaining patients demonstrated dysphagia characterized by laryngeal penetration (83%) and/or direct aspiration (50%). The most common findings were laryngeal edema (29%), anterior displacement of glottis structures (14%), and cobblestoning (11%). There was no morbidity directly associated with the procedure. No cyanosis or respiratory distress occurred during or immediately after the procedure.
Conclusion:
Performing FEES exams on breastfeeding infants is safe and effective. There is no other instrumental evaluation of swallowing to assess dysphagia in this population.
Level Of Evidence:
4. Laryngoscope, 126:1681-1686, 2016.
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