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Updated: Apr 3, 2026

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
Licit and Illicit Substance Use by Adolescent E-Cigarette Users Compared with Conventional Cigarette Smokers, Dual
Alfgeir L Kristjansson1, Michael J Mann2, Inga Dora Sigfusdottir3
1Department of Social and Behavioral Sciences, School of Public Health, West Virginia University, Morgantown, West Virginia; Icelandic Center for Social Research and Analysis, Reykjavik University, Reykjavik, Iceland.
Purpose:
Compare the lifetime prevalence of eight forms of substance use (alcohol, drunkenness, oral tobacco, snuff, sleeping pills/tranquilizers, sniffed glue, marijuana, and amphetamine) among adolescent e-cigarette (EC) users, conventional cigarette (CC) smokers, dual users, and nonusers.
Methods:
We analyzed population-level school-survey data collected from 10th-grade students (aged 15-16 years) in February 2015 in Iceland (N = 3,477; response rate, 84.4%).
Results:
Smoking rates were similar for both sexes. Around 17% had used ECs and almost 8% had used ECs and not combustible tobacco, 5%-6% had smoked CCs but not ECs, around 9% were dual users. EC-only users were significantly more likely than nonusers to have used the eight substances investigated in the study but were less likely to have used these substances than CC smokers and dual users.
Conclusion:
The four groups assessed in this study appear to form a sequential risk gradient to the use of other substances.
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