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Related Experiment Videos

Intraglomerular embolization by tubular cells.

T Tóth1, L Antal, J Rédl

  • 1Department of Pathology, County Hospital, Szolnok, Hungary.

International Urology and Nephrology
|January 1, 1989
PubMed
Summary

Intraglomerular embolization by tubular epithelial cells is a rare finding in renal biopsies. This artefact involves cells appearing within glomerular capillaries or urinary spaces.

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Area of Science:

  • Nephrology
  • Pathology
  • Histology

Background:

  • Renal biopsy is a critical diagnostic tool.
  • Artefacts can complicate interpretation of biopsy specimens.
  • Tubular epithelial cells are typically found outside glomeruli.

Purpose of the Study:

  • To report the occurrence and characteristics of intraglomerular embolization by tubular epithelial cells.
  • To highlight this rare artefact in renal needle biopsy specimens.

Main Methods:

  • Review of 300 consecutive renal biopsy cases.
  • Identification and documentation of intraglomerular tubular epithelial cells.
  • Analysis of cell location within the glomerulus.

Main Results:

  • The phenomenon was observed in 5 out of 300 renal biopsy cases (1.67%).
  • Tubular epithelial cells were found within glomerular capillaries in two cases.
  • Cells were located in both glomerular capillaries and the urinary space in three cases.

Conclusions:

  • Intraglomerular embolization by tubular epithelial cells is a rare but identifiable artefact.
  • Awareness of this artefact is important for accurate renal biopsy interpretation.
  • This finding may be relevant in specific clinical or pathological contexts.

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