Related Experiment Video
Updated: Apr 3, 2026

Mouse Models Of Helicobacter Infection And Gastric Pathologies
Published on: October 18, 2018
Gastric Microbiota
Gianluca Ianiro1, Javier Molina-Infante2, Antonio Gasbarrini1
1Division of Internal Medicine, Gastroenterology and Liver Disease, Department of Internal Medicine, "A. Gemelli" University Hospital, Rome, Italy.
Abstract:
After the discovery of Helicobacter pylori in 1983, the stomach was no longer considered a sterile environment. In 2015, evolving data shows that H. pylori is not the only inhabitant of the gastric mucosa. Using culture-independent methods of analysis, a non-H. pylori microbial community has been recently observed in the human stomach, the so-called human gastric microbiota, along with H. pylori itself. Increasing evidence supports the hypothesis that although H. pylori may be the most relevant, it is not the only local bacterial culprit leading to gastric diseases. Further studies are warranted to offer a better picture of the role and functions of gastric microbiota and to identify the best therapeutic modulators of gut microbiota for the management of gastric diseases.
Related Concept Videos
Microbiota of the Stomach and Small Intestine
Microbiota of the Large Intestine
What is Monogastric Digestion?
Functions of the Gut Microbiota
Introduction to the Human Microbiota
Development of Human Microbiota

