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Updated: Apr 3, 2026

An Intravital Microscopy-Based Approach to Assess Intestinal Permeability and Epithelial Cell Shedding Performance
Published on: December 3, 2020
[Multiple small bowel perforations due to Behcet's disease]
1Department of General Surgery, Near East University Faculty of Medicine, Nicosia, Northern Cyprus. tevfikeker@yahoo.com.
Behcet
Area of Science:
- Gastroenterology
- Immunology
- Surgery
Background:
- Behcet's disease is a rare inflammatory disorder affecting multiple body systems.
- Gastrointestinal involvement, particularly in the ileocecal region, is common, often presenting as ulcers.
- Intestinal perforation is a serious, though infrequent, complication of Behcet's disease.
Observation:
- A 19-year-old male presented with acute abdomen due to Behcet's disease.
- Laparotomy revealed multiple perforations in the terminal ileum.
- The patient underwent partial ileum resection and ileostomy closure.
Findings:
- Multiple ileum perforations represent an unusual presentation of Behcet's disease.
- Surgical intervention can effectively manage intestinal perforations in Behcet's disease.
- The patient experienced an uneventful recovery and remained well during follow-up.
Implications:
- Highlights the potential for severe gastrointestinal complications in Behcet's disease.
- Emphasizes the importance of early diagnosis and surgical management for intestinal perforations.
- Contributes to the literature on rare manifestations of Behcet's disease.
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