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Outbreak of Botulism After Consumption of Illicit Prison-Brewed Alcohol in a Maximum Security Prison--Arizona, 2012
Seema Yasmin1, Laura Adams2, Graham Briggs3
1Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA Arizona Department of Health Services, Phoenix, AZ, USA seemayasmin@gmail.com.
Abstract:
The authors investigated the second botulism outbreak to occur in a maximum security prison in Arizona within a 4-month period. Botulism was confirmed in eight men aged 20 to 35 years who reported sharing a single batch of pruno made with potatoes. Initial symptoms included blurred vision, slurred speech, muscle weakness, ptosis, and dysphagia. All patients received heptavalent botulinum antitoxin, seven required mechanical ventilation, and all survived. The median incubation period was 29 hours. Sera from all patients and leftover pruno tested positive for botulinum toxin type A. Botulism should be considered among prisoners with cranial nerve palsies and descending, symmetric flaccid paralysis. Prison-brewed alcohol, particularly when made with potatoes, can be a vehicle for botulism and is associated with outbreaks of botulism in prisons.
Insights
A prison botulism outbreak linked to homemade potato pruno affected eight men. Prompt treatment with antitoxin and ventilation ensured all survivors, highlighting risks of prison-brewed alcohol.
Area of Science:
- Toxicology
- Infectious Diseases
- Public Health
Background:
- Botulism outbreaks pose significant public health risks, particularly in closed environments like prisons.
- Contaminated homemade alcoholic beverages, such as pruno, are known vehicles for botulism.
- This study examines a second botulism outbreak in an Arizona maximum-security prison within a short timeframe.
Purpose of the Study:
- To investigate the cause and characteristics of a botulism outbreak in a maximum-security prison.
- To identify the source of botulism toxin and understand transmission dynamics.
- To emphasize the importance of considering botulism in differential diagnoses for prisoners presenting with specific neurological symptoms.
Main Methods:
- Case-finding and clinical assessment of eight affected male prisoners.
- Laboratory analysis of patient sera and suspected pruno for botulinum toxin type A.
- Epidemiological investigation into shared consumption of homemade alcohol (pruno).
Main Results:
- Eight adult males (aged 20-35) were diagnosed with botulism.
- All patients consumed a single batch of potato-based pruno.
- Botulinum toxin type A was detected in patient sera and the pruno; all patients survived after treatment.
Conclusions:
- Prison-brewed alcohol, especially when made with potatoes, can be a potent source of botulism outbreaks.
- Botulism should be a key consideration for prisoners exhibiting cranial nerve palsies and descending paralysis.
- Early administration of heptavalent botulinum antitoxin and supportive care are critical for patient survival.
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