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Updated: Apr 3, 2026

Procurement and Perfusion-Decellularization of Porcine Vascularized Flaps in a Customized Perfusion Bioreactor
Published on: August 1, 2022
Thinned chimeric radial collateral artery perforator flap in complex distal thumb reconstruction
Dajiang Song1,2, Xiangwu Deng3, Yanmin Chen3
1Department of Head and Neck Surgery, Department of Oncology Plastic Surgery, Hunan Province Cancer Hospital of Xiangya Medical School, Central South University, Changsha, China.
Reconstructing thumb bone and soft tissue defects is challenging. Thinned chimeric radial collateral artery perforator flaps offer a successful microsurgical solution, improving function and appearance.
Area of Science:
- Microsurgery
- Orthopedic surgery
- Plastic surgery
Background:
- Thumb defects involving bone and soft tissue present significant reconstruction challenges.
- Traditional surgical methods often yield unsatisfactory outcomes for these complex cases.
Purpose of the Study:
- To evaluate the efficacy of thinned chimeric radial collateral artery (RCA) perforator flaps for thumb reconstruction.
- To assess functional and cosmetic outcomes following this microsurgical technique.
Main Methods:
- Microsurgical reconstruction using 13 thinned chimeric RCA perforator flaps with thinned skin paddles and humeral bone segments.
- Inclusion of the posterior cutaneous nerve of the arm for sensory restoration.
- Evaluation of defect and flap sizes, bone fragment dimensions, and post-operative outcomes including Kapandji opposition score and two-point discrimination.
Main Results:
- All flaps survived, with bone union achieved in all cases. Average flap thickness post-defatting was 3.5 mm.
- Mean thumb opposition score was 6, and mean sensation recovery was 7.5 mm.
- Cosmetically acceptable results were achieved, with no further flap revisions needed.
Conclusions:
- Thinned chimeric RCA perforator flaps represent a beneficial microsurgical alternative for complex thumb defects.
- This technique effectively addresses both bone and soft tissue loss, offering a viable solution where traditional methods fall short.
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