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Published on: June 12, 2020
Attention deficit and hyperactivity disorder and infantile colic
N Kaymaz1, M E Uzun, S Cevizci
1Çanakkale Onsekiz Mart University, Faculty of Medicine, Department of Pediatrics, Çanakkale, Turkey - sulesln@yahoo.com.
Infantile colic (IC) is more common in children with Attention Deficit Hyperactivity Disorder (ADHD), suggesting a shared neurochemical origin. Early monitoring of infants with IC may help identify those at risk for ADHD.
Area of Science:
- Neuroscience
- Pediatrics
- Child Psychiatry
Background:
- Attention Deficit Hyperactivity Disorder (ADHD) and Infantile Colic (IC) are complex conditions with unknown etiologies.
- Neurotransmitter metabolism maldevelopment in the central nervous system is hypothesized for both disorders.
Purpose of the Study:
- To investigate the potential relationship between Infantile Colic and ADHD.
- To explore a possible common etiological factor involving neurochemical developmental issues.
Main Methods:
- A case-control study involving 114 children diagnosed with ADHD and 149 healthy controls.
- Utilized Conners Parent and Teacher Rating Scales and DSM-IV criteria for ADHD assessment.
- Infantile Colic diagnosed using Wessel's modified criteria; parental surveys were administered.
Main Results:
- The prevalence of IC was significantly higher in the ADHD group (50.0%) compared to the non-ADHD group (30.2%) (P=0.001).
- Mean ages of the ADHD and control groups were comparable (10.14±2.48 and 9.94±2.34 years, respectively).
- The duration of IC did not differ significantly between the groups (P=0.143).
Conclusions:
- Infantile Colic may serve as a postnatal risk factor and marker for childhood ADHD.
- A shared underlying neurochemical mechanism may link IC and ADHD.
- Infants experiencing IC warrant closer examination and follow-up for potential ADHD development.
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