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Successful Treatment of Peritoneal Dialysis Catheter-Related Polymicrobial Peritonitis Involving Clostridium

Sheena Bharti1, Prashant Malhotra2, Stefan Juretschko3

  • 1Department of Infectious Diseases, Hoftstra North Shore-LIJ School of Medicine, Manhasset, New York, USA sbharti@nshs.edu.

Journal of Clinical Microbiology
|September 18, 2015
PubMed

Insights

Clostridium difficile infections (CDI) can cause rare abdominal issues. This case study details the first successful treatment of catheter-related CDI peritonitis in a peritoneal dialysis patient.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Nephrology

Background:

  • Clostridium difficile is a leading cause of nosocomial infections.
  • Antimicrobial use is a primary risk factor for C. difficile infection.
  • Extraintestinal C. difficile manifestations are infrequently documented.

Observation:

  • A patient undergoing peritoneal dialysis developed peritonitis.
  • The peritonitis was attributed to Clostridium difficile.
  • This represented a rare extraintestinal manifestation of the pathogen.

Findings:

  • The case involved catheter-related Clostridium difficile peritonitis.
  • The patient received successful treatment for the condition.
  • This marks the first reported successful treatment for this specific complication.

Implications:

  • Highlights the potential for rare C. difficile manifestations in immunocompromised or vulnerable patient populations.
  • Suggests the need for vigilance in diagnosing C. difficile peritonitis in peritoneal dialysis patients.
  • Informs treatment strategies for unusual C. difficile presentations.

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