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Aggregation-based detection of M. smegmatis using D-arabinose-functionalized fluorescent silica nanoparticles
Kalana W Jayawardana1, Samurdhi A Wijesundera, Mingdi Yan
1Department of Chemistry, University of Massachusetts Lowell, Lowell, MA 01854, USA. mingdi_yan@uml.edu.
Chemical Communications (Cambridge, England)
|September 18, 2015
Abstract:
Fluorescein-doped silica nanoparticles (FSNPs) functionalized with D-arabinose (Ara) showed strong interactions with Mycobacterium smegmatis (M. smegmatis) and caused the bacteria to aggregate. This aggregate formation was used as a means to detect M. smegmatis at the concentration of 10(4) CFU per mL.
