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Intervention Effect of Electroacupuncture Combined with EPCs Transplantation on the Mice in Aging Model
1Institute of Acupuncture and Moxibustion, Chinese Academy of Chinese Medical Sciences, Beijing 100700, China ; Affiliated Hospital of Inner Mongolia University for Nationalities, Tongliao 028000, China.
Abstract:
The results of this experiment suggested that electroacupuncture promotes the endothelialization of liver endothelial progenitor cells (EPCs) for mice in D-gal model and improves the repair of vascular endothelial function, as well as increasing the vascular endothelial growth factor (VEGF) expression in liver tissue fluorescence and KL protein levels. Also, it reduces the malondialdehyde (MDA) activity and delays vascular aging and even overall aging. Results showed that the in vivo fluorescence intensity for D-gal EA group was significantly lower than that of D-gal group, P < 0.05; VEGF fluorescence expression in liver tissue for D-gal EA group was significantly higher than that for D-gal group, P < 0.05; KL protein content in liver tissue for D-gal EA group was significantly higher than that for D-gal group, P < 0.05; MDA activity for D-gal EA group was significantly lower than that for D-gal group, P < 0.05.
