[Whole blood, chemiluminescence in patients with periapical granuloma]

Spontaneous and mannozyme-induced whole blood chemiluminescence was studied in 14 patients with chronic periapical granuloma. Investigations were performed before surgery and 7 days as well as 3 months after apicectomy. Spontaneous chemiluminescence was significantly higher in patients versus normal controls. The elevated spontaneous chemiluminescence decreased significantly after surgery. Results indicate that, in these patients, granulocytes are in a metabolically and functionally activated state in vivo.