Related Experiment Video
Updated: Apr 3, 2026
Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
Published on: September 8, 2023
Bone structure and turnover in postmenopausal women with type 2 diabetes mellitus
Farideh Razi1, Mahnaz Esmaili, Ensieh Nasli Esfahani
11Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran 2Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran 3Department of Community Medicine, Alborz University of Medical Sciences, Karaj, Iran 4Department of Epidemiology and Biostatistics, Iran University of Medical Sciences, Tehran, Iran 5Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran 6Department of Health Sciences Education Development, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 7Center for Microsystems Technology, Imec and Ghent University, Gent-Zwijnaarde, Belgium 8Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Objective:
Considering the high prevalence of diabetes and osteoporosis in Iranians, the current research was conducted to study the correlation between these two diseases in a group of postmenopausal women.
Methods:
The present study was conducted on postmenopausal women recruited in the third phase of the Iranian Multi-centric Osteoporosis Study. They were divided into two groups (diabetic and nondiabetic) based on their diabetes history and laboratory results. The serum levels of bone markers and bone mineral density values were compared between the two groups.
Results:
A total of 110 postmenopausal women were included. Although bone mineral density values were nonsignificantly higher in diabetic postmenopausal women, there was no considerable difference between the prevalence of osteoporosis or serum levels of bone markers in the two groups.
Conclusions:
There is no difference in bone mass values or bone turnover process between Iranian postmenopausal women with or without diabetes.
More Related Videos
02:08Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis
Published on: July 5, 2024
07:22Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
Published on: March 7, 2025
Related Concept Videos
01:29Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
01:40Bone Remodeling
01:31Osteoclasts in Bone Remodeling
01:02What is the Skeletal System?
01:31Bone Remodeling and Repair
01:25Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...