Uniocular proptosis in children

Area of Science:

• Ophthalmology
• Pediatric Medicine
• Radiology

Background:

• Uniocular proptosis, or bulging of one eye, is a significant clinical sign in children.
• Accurate diagnosis is crucial for appropriate management and preventing long-term complications.
• Etiologies range from benign to malignant conditions affecting the orbit, periorbital tissues, or intracranial structures.

Purpose of the Study:

• To review the clinical, radiological, and pathological features of uniocular proptosis in a pediatric cohort.
• To evaluate the diagnostic accuracy of various imaging modalities.
• To discuss the management strategies for different types of orbital, periorbital, and intracranial lesions causing proptosis.

Main Methods:

• Retrospective analysis of 80 pediatric patients diagnosed with uniocular proptosis.
• Review of clinical presentations, imaging findings (radiological), and histopathological results (pathological).
• Correlation of lesion location (orbital, periorbital, intracranial) with clinical outcomes and management.

Main Results:

• Orbital lesions were the most common cause (57 cases) of uniocular proptosis in children.
• Periorbital lesions accounted for 19 cases, and intracranial lesions for 4 cases.
• The study highlights the diverse origins of proptosis, emphasizing the need for comprehensive evaluation.

Conclusions:

• Uniocular proptosis in children necessitates a thorough investigation to differentiate between orbital, periorbital, and intracranial pathologies.
• Integrated clinical, radiological, and pathological assessment is vital for accurate diagnosis.
• Timely and appropriate management based on the underlying cause improves patient outcomes.