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Published on: May 16, 2025
[New populations at increased cardiovascular risk: Cardiovascular disease in dermatological diseases]
Elena Godoy-Gijón1, Carmen Meseguer-Yebra2, Lucía Palacio-Aller3
1Servicio de Dermatología, Hospital Clínico Universitario de Valladolid, Valladolid, España.
Insights
Cardiovascular risk is elevated in certain skin conditions like psoriasis. Clinicians should monitor cardiovascular risk factors in patients with dermatological diseases, even those not yet in guidelines.
Area of Science:
- Dermatology
- Cardiology
- Public Health
Background:
- Increased cardiovascular risk is recognized in some dermatological diseases.
- Psoriasis and systemic lupus erythematosus are included in cardiovascular disease prevention guidelines.
- Emerging evidence links other skin conditions to heightened cardiovascular risk.
Purpose of the Study:
- To review evidence associating dermatological diseases with cardiovascular risk.
- To highlight the need for cardiovascular risk factor management in affected patients.
- To inform clinicians about less recognized dermatological conditions with potential cardiovascular implications.
Main Methods:
- Literature review of studies on dermatological diseases and cardiovascular risk.
- Analysis of current cardiovascular disease prevention guidelines.
- Synthesis of evidence linking specific dermatological conditions to cardiovascular outcomes.
Main Results:
- Psoriasis and systemic lupus erythematosus are established risk factors.
- Androgenic alopecia, polycystic ovary syndrome, hidradenitis suppurativa, and lichen planus show significant associations with increased cardiovascular risk.
- These latter conditions are not yet incorporated into major cardiovascular guidelines.
Conclusions:
- Clinicians must be vigilant for cardiovascular risk in patients with various dermatological diseases.
- Proactive management of cardiovascular risk factors is crucial for patients with conditions like androgenic alopecia and hidradenitis suppurativa.
- Guidelines should consider expanding to include a broader range of dermatological diseases associated with cardiovascular risk.
Abstract:
The increased cardiovascular risk in some dermatological diseases has been demonstrated in recent decades. Diseases such as psoriasis and systemic lupus erythematosus are currently included in the guidelines for prevention of cardiovascular disease. Other diseases such as androgenic alopecia, polycystic ovary syndrome, hidradenitis suppurativa or lichen planus have numerous studies that point to an increased risk, however, they have not been included in these guidelines. In this article we review the evidence supporting this association, in order to alert the clinician to the need for greater control in cardiovascular risk factors in these patients.
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